The Frontline of Innate Immunity: ORA ORA ORA! Unraveling the Body's Defense System
- KAZ KOBAYASHI
- 2024年6月28日
- 読了時間: 2分
"Yare yare daze, another talk about immunity…" But don't let your guard down! Innate immunity is the body's first line of defense, swiftly eliminating foreign invaders like a stand user taking down enemies. Coughs, sneezes, tears, and even diarrhea are all powerful reactions designed to expel intruders from the body. Just like a stand's punch, these reactions are rapid and effective.

The Strategy of Mucous Membranes: Lysozyme and Mucin
At the forefront of innate immunity is the mucous membrane. This barrier is equipped with "lysozyme," an enzyme that breaks down proteins and neutralizes intruders. Mucin, another key component, traps foreign particles and expels them through ciliary movement. This teamwork is reminiscent of the Joestar family's coordinated attacks.
Immune Tolerance: Recognizing Friend from Foe
Not all foreign substances trigger an immune response, thanks to "immune tolerance." This mechanism allows us to safely consume food without overreacting. However, when immune tolerance fails, allergies occur. It's like a stand losing control and attacking everything indiscriminately.
Beyond the Mucous Membranes: Macrophages and NK Cells
When invaders breach the mucous membrane, cells like macrophages, neutrophils, dendritic cells, and NK cells step in. These cells, akin to stands, swiftly identify and attack foreign entities. NK cells, for instance, destroy invaders without prior activation, embodying the spirit of "ORA ORA ORA!"
The Importance of Ketone Bodies: Brain's Energy Source
Ketone bodies are a crucial energy source, especially during starvation. Recent research shows that the brain can derive a significant portion of its energy from ketone bodies, similar to how a stand user finds strength in adversity.
Ketosis and Ketoacidosis
Ketosis, where the body uses ketone bodies for energy, can be beneficial. However, excessive ketosis can lead to ketoacidosis, a dangerous condition, particularly for diabetics. Nonetheless, a typical low-carb diet is generally safe.
Conclusion: Understanding the Power of Innate Immunity
Innate immunity is a formidable defense system. From mucous membranes to macrophages and NK cells, the body's ability to eliminate foreign invaders is akin to a stand's power. Understanding these mechanisms helps us better protect our health.

