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GYM CONQUER ジム筋華のブランドイメージ

The Battle Between Fructose and Belly Fat

"Good grief..." As men age, many find their belly growing, not just from weakened transverse abdominis muscles but from the accumulation of fat. This invisible enemy, much like a stand, creeps up on you. But by understanding this foe and learning how to fight back, you can defy fate!

Dynamic illustration of a character inspired by Jolyne Cujoh from JoJo's Bizarre Adventure, in her iconic JoJo pose. She has long, light green hair styled in two buns with loose strands and wears a green patterned outfit. She strikes a dramatic pose with her body twisted and one arm outstretched, surrounded by stylized cortisol molecules and fructose structures. The background features swirling energy and glowing elements, symbolizing metabolic processes and the battle against fat accumulation. English onomatopoeia like 'ORA ORA' and 'MENACING' add to the intense atmosphere. The scene is vibrant, colorful, and dramatic, capturing the essence of a JoJo-style confrontation.

The Role of Cortisol in Belly Fat

The increase in belly fat is linked to central obesity, a side effect of adrenal corticosteroids, primarily due to cortisol. This hormone is reactivated in the liver, fat tissue, and omentum, promoting fat accumulation. Cortisol also boosts appetite and activates fatty acid synthase (FAS). "This invisible enemy is a tough one!"

The Role of NADPH and 11βHSD1

Here's the crux of the matter: how carbohydrate restriction affects cortisol. NADPH, present in cells, impacts the enzyme 11βHSD1. When carbohydrates are restricted, NADPH levels drop, reducing 11βHSD1 activity and cortisol. However, fructose intake negates this benefit!

The Impact of Fructose

Fructose bypasses phosphofructokinase, leading to increased triglycerides. In fat cells, fructose is converted to fructose-6-phosphate, which enhances 11βHSD1 activity. Consequently, belly fat and free fatty acids increase. "This invisible enemy keeps getting stronger!"

Research on Rats

Studies on rats show that diets high in fructose increase appetite, belly fat, and cortisol receptors. Chronic stress and fructose intake also boost 11βHSD1 expression, exacerbating fat synthesis.



Fructose should be avoided during moderate carbohydrate restriction. Even small amounts prevent the reduction of cortisol. Bodybuilders and health-conscious individuals should limit fructose intake, especially on cheat days. "Good grief... but now we see the way to defy fate!"

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